The Effects of Coronary Vasodilators upon Coronary and Pulmonary Circulation : Symposium on Coronary Vasodilators

Antiarrhythmic effects of coronary vasodilators on canine ventricular arrhythmia models.

Antiarrhythmic effects of intravenous coronary vasodilators (verapamil, diltiazem, bepridil, trimetazidine and nicorandil) were evaluated using two canine ventricular arrhythmia models (halothane-adrenaline arrhythmia and digitalis arrhythmia), and the minimum effective plasma concentrations of the drugs were determined for each arrhythmia model. Verapamil (0.1 mg/kg), diltiazem (0.1 mg/kg), be...

Effects of epinephrine, acetylcholine and vasodilators on the coronary blood flow of atherosclerotic rabbits.

In the studies on coronary circulation mostly normal animals have been subjected to the experimental investigation. It seems important to investigate the effects of drugs on the coronary vascular bed in animals with atherosclerosis. Rinzler et al. (1) demonstrated that in atherosclerotic rabbits intravenous ergonovine produced electrocardiographic changes characteristic of coronary insufficienc...

Pulmonary vasodilators.

Pulmonary vasodilators are an important treatment for pulmonary arterial hypertension. They reduce pulmonary artery pressure; improve hemodynamic function; alter ventilation/perfusion matching in the lungs; and improve functional quality of life, exercise tolerance, and survival in patients with severe pulmonary arterial hypertension. This paper reviews the currently available pulmonary vasodil...

Vasodilators in pulmonary hypertension.

Comparison of the Graft Angles Effects on the Temporal Wall Shear Stress Gradients in the Aorto-Coronary and Coronary-Coronary Bypasses

In this theoretical study, the effect of various types of bypass graft angles on the flow field, has been investigated specially on the temporal Wall Shear Stress (WSS) on the toe, heel and some locations on the bed of the Left Anterior Descending (LAD) artery at the anastomoses areas in the Aorto-Coronary (AC) and Coronary-Coronary (CC) bypasses. Flow fields in both bypasses with angles of...